Immunoglobulin-M estimation and C-reactive protein detection in neonatal septicemia.

Autor: Krishna BV; Department of Microbiology, Karnatak Institute of Medical Sciences Hubli-580 002, Karnataka., Nadgir SD, Tallur SS
Jazyk: angličtina
Zdroj: Indian journal of pathology & microbiology [Indian J Pathol Microbiol] 2000 Jan; Vol. 43 (1), pp. 35-40.
Abstrakt: Immunoglobulin-M estimation, and C-Reactive Protein test and blood culture were performed on 57 neonates, clinically suspected to have septicemia. IgM level of > or = 20 mg/dl was found in 58.62% cases and CRP test was positive in 68.98% of culture proven sepsis. Blood culture was positive in 29 cases, with the predominant organism being Klebsiella. Of the 2 tests, CRP had a higher sensitivity (68.97%) while IgM estimation had a higher specificity (82.14%). When the 2 tests were considered together the sensitivity and specificity further increased. Death rate among neonates with IgM levels < 20 mg/dl was 5 times higher than those with elevated IgM levels.
Databáze: MEDLINE