A synthetic overview of new molecules with 5-HT1A binding affinities.

Autor: Pessoa-Mahana H; Departamento de Química Orgánica y Fisicoquímica. Facultad de Ciencias Químicas y Farmacéuticas. Universidad de Chile. Olivos 1007.Casilla 233. Santiago 1. Chile. hpessoa@ll.ciq.uchile.cl, Araya-Maturana R, Saitz CB, Pessoa-Mahana DC
Jazyk: angličtina
Zdroj: Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2003 Mar; Vol. 3 (2), pp. 77-93.
DOI: 10.2174/1389557033405278
Abstrakt: The present review discusses the synthetic strategies of new ligands exhibiting mainly 5-HT(1A)binding affinities. Specifically we focused our attention in the synthesis of compounds structurally related to arylpiperazine, 2-aminotetralin, and benzopyran derivatives.
Databáze: MEDLINE