| Autor: |
Bolton WK, Atuk NO, Rametta C, Sturgill BC, Spargo BH |
| Jazyk: |
angličtina |
| Zdroj: |
Clinical nephrology [Clin Nephrol] 1976 Feb; Vol. 5 (2), pp. 88-91. |
| Abstrakt: |
A patient presented with a 6 month history of progessive renal failure. Serum creatinine was 7.1 mg/100 ml, creatinine clearance 4 ml/minute and hematocrit 22%. Skin tests for tuberculosis, trichophyton, SK/SD and candida were all unreactive and all cultures were negative or showed normal growth. A renal biopsy revealed non-caseating epithelial granulomas and foreign body multinucleated giant cells. No deposits or micro-organisms were seen on electron microscopy. Bone marrow and lymph node biopsies were unremarkable and no lung pathology was present. Therapy with systemic prednisone produced a dramatic improvement with serum creatinine diminishing to 1.3 mg/100 ml, creatinine clearance increasing to 81 ml/minute and hematocrit improving to 39%. A search of the literature has failed to reveal similar reports of reversible renal failure from isolated granulomatous renal sarcoidosis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
