Effect of lipid matrix and cytoskeleton proteins on Ca2+-activated K+ channels in erythrocytes of alcoholic and II type diabetes mellitus patients.

Autor: Prokop'eva VD; Siberian State Medical University, Tomsk, Russia., Petrova IV, Sitozhevskii AV, Kremeno SV, Koryukin VI, Baskakov MB, Bokhan NA, Novitskii VV
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2002 Oct; Vol. 134 (4), pp. 345-8.
DOI: 10.1023/a:1021948012581
Abstrakt: We studied the effect of changes in erythrocyte volume and irreversible thermal denaturation of cytoskeleton proteins and lipid matrix on activity of Ca(2+)-activated K+ channels in erythrocytes of alcoholic and patients with II type diabetes mellitus. Changes in Ca(2+)-dependent potassium permeability of erythrocyte membrane in alcoholic patients and patients with II type diabetes mellitus are related to modification of cytoskeleton, rather than to changes in lipid matrix.
Databáze: MEDLINE