| Autor: |
Zakhidov ST; Biological Faculty and Institute of Mechanics, Moscow State University, Vorob'evy gory, Moscow, 119992 Russia., Marshak TL, Uryvaeva IV, Gopko AV, Semenova ML, Delone GV, Mikhaleva IaIu, Makarov AA |
| Jazyk: |
ruština |
| Zdroj: |
Ontogenez [Ontogenez] 2002 Nov-Dec; Vol. 33 (6), pp. 444-56. |
| Abstrakt: |
It was shown that during ontogenesis, the mice prone to (SAMP1) and resistant against accelerates senescence did not differ substantially in the frequency of cytogenetic aberrations in the hepatocytes and spermatogenic cells (spermatozoa and circular spermatids). These data suggest that in the mice of both lines, the processes of appearance, development, and functioning of complex biological systems, such as liver and testis, take place against the background of high genetic instability. The role of genetic instability in senescence is discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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