Phase II and pharmacologic study of weekly oral paclitaxel plus cyclosporine in patients with advanced non-small-cell lung cancer.
Autor: | Kruijtzer CM; Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Schellens JH, Mezger J, Scheulen ME, Keilholz U, Beijnen JH, Rosing H, Mathôt RA, Marcus S, van Tinteren H, Baas P |
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Jazyk: | angličtina |
Zdroj: | Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2002 Dec 01; Vol. 20 (23), pp. 4508-16. |
DOI: | 10.1200/JCO.2002.04.058 |
Abstrakt: | Purpose: A phase II study was performed to assess the efficacy and toxicity of oral cyclosporine (CsA) plus paclitaxel in advanced non-small-cell lung cancer (NSCLC). Patients and Methods: Chemotherapy-naive or previously treated patients (one regimen) with measurable disease and World Health Organization performance status Conclusion: Oral paclitaxel plus CsA is active and safe in advanced NSCLC, including in patients previously treated with chemotherapy. |
Databáze: | MEDLINE |
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