The role of parotid biopsy in the diagnosis of pediatric Sjögren syndrome.
| Autor: | McGuirt WF Jr; Department of Otolaryngology, Wake Forest University Baptist Medical Center, Winston-Salem, NC 27157-1034, USA., Whang C, Moreland W |
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| Jazyk: | angličtina |
| Zdroj: | Archives of otolaryngology--head & neck surgery [Arch Otolaryngol Head Neck Surg] 2002 Nov; Vol. 128 (11), pp. 1279-81. |
| DOI: | 10.1001/archotol.128.11.1279 |
| Abstrakt: | Objectives: To describe our experience with primary and secondary Sjögren syndrome (SS) in the pediatric population and to evaluate the effectiveness of parotid gland biopsy in the diagnosis of pediatric SS. Design: Case series review of 6 pediatric patients evaluated during a 4-year period with varied head and neck manifestations of SS. Setting: Tertiary care children's hospital. Patients: Six children (4 boys and 2 girls) ranging in age from 6 to 12 years, who were diagnosed as having primary or secondary SS. Intervention: Six minor salivary gland and 4 parotid gland biopsies for pathologic examination. Main Outcome Measures: Pathologic examination of salivary tissue consistent with SS. Results: All 6 patients underwent minor salivary gland biopsy, 2 (33%) were consistent with SS, while the remaining 4 (67%) were nondiagnostic. The 4 patients with nondiagnostic minor salivary gland biopsy results went on to have parotid biopsies, of which all 4 had histologic findings consistent with SS. No complications were encountered. Conclusion: Parotid gland biopsy is an effective and safe means of obtaining salivary gland tissue for histologic evaluation of SS in the pediatric population. |
| Databáze: | MEDLINE |
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