| Autor: |
Graadt van Roggen JF; Leids Universitair Medisch Centrum, afd. Pathologie, Postbus 9600, 2300 RC Leiden., Hogendoorn PC |
| Jazyk: |
Dutch; Flemish |
| Zdroj: |
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2002 Oct 26; Vol. 146 (43), pp. 2022-6. |
| Abstrakt: |
Soft tissue tumours are rare and form some of the most difficult pathological subjects in medicine. The diagnosis of a soft tissue tumour goes hand-in-hand with a number of clinically relevant questions related to the therapy and prognosis (what is the classifying diagnosis?, is the proliferation reactive or neoplastic?; in the case of neoplasia: is it benign or malignant?, what is the grade of malignancy?, what is the expected clinical course?). Due to new insights in tumour diversity at a morphologic level, developments in immunohistochemistry and increasing (cyto)genetic knowledge about tumour-specific abnormalities, the known histological groups of tumours have been better characterised at the clinicopathological level, new tumour entities have been defined, old terms have been abandoned and a better understanding of tumour histogenesis has been established. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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