Coronary artery bypass in patients 80 years and over: is off-pump the operation of choice?

Autor: Hoff SJ; St. Thomas Heart Institute, St. Thomas Hospital, Nashville, Tennessee, USA. shoff@csapc.net, Ball SK, Coltharp WH, Glassford DM Jr, Lea JW 4th, Petracek MR
Jazyk: angličtina
Zdroj: The Annals of thoracic surgery [Ann Thorac Surg] 2002 Oct; Vol. 74 (4), pp. S1340-3.
DOI: 10.1016/s0003-4975(02)03913-9
Abstrakt: Background: Octogenarians are at increased risk for perioperative morbidity and mortality after coronary artery bypass. In this study we compared our experience with patients undergoing on-pump coronary artery bypass (CAB) and those undergoing off-pump coronary artery bypass (OPCAB) to assess outcomes.
Methods: We used hospital database analysis in patients 80 years and older who underwent nonemergent coronary artery bypass with (N = 169) and without (N = 60) cardiopulmonary bypass from January 1999 through June 2001.
Results: Both groups were at increased perioperative risk based on the Society of Thoracic Surgeons risk model (7.7% OPCAB vs 5.8% CAB, p = 0.03). There were no operative deaths in the OPCAB group but there were eight (4.7%) in the CAB group (p = NS). Perioperative stroke (0% OPCAB vs 7.1% CAB, p = 0.04), prolonged ventilation (1.7% OPCAB vs 11.8% CAB, p = 0.02), and transfusion rate (33% OPCAB vs 70.4% CAB, p < 0.001) were all lower in the OPCAB group. A shorter hospital stay (6.3 days OPCAB vs 11.5 days CAB, p < 0.001) resulted in lower hospital cost in the OPCAB group ($9,363 OPCAB vs $12,312 CAB, p < 0.001).
Conclusions: In this study, off-pump coronary artery bypass grafting in elderly patients was associated with fewer complications, a shorter hospital stay, and lower hospital cost. Off-pump coronary artery bypass grafting may be the operation of choice for octogenarians requiring surgical myocardial revascularization.
Databáze: MEDLINE