Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian hospitals reveals a limited diversity of gene cassette arrays.

Autor: Gombac F; Dipartimento di Scienze Biomediche, Sezione di Microbiologia, Università di Trieste, I-34127 Trieste, Italy., Riccio ML, Rossolini GM, Lagatolla C, Tonin E, Monti-Bragadin C, Lavenia A, Dolzani L
Jazyk: angličtina
Zdroj: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2002 Nov; Vol. 46 (11), pp. 3665-8.
DOI: 10.1128/AAC.46.11.3665-3668.2002
Abstrakt: Integron carriage by 36 epidemiologically unrelated Acinetobacter baumannii isolates collected over an 11-year period from patients in six different Italian hospitals was investigated. Sixteen type 1 integron-positive isolates (44%) were found, 13 of which carried the same array of cassettes, i.e., aacC1, orfX, orfX', and aadA1a. As ribotype analysis of the isolates demonstrated a notable genetic diversity, horizontal transfer of the entire integron structure or ancient acquisition was hypothesized.
Databáze: MEDLINE