| Autor: |
Lapchinskaia OA, Saburova TP, Siniagina OP, Konstantinova NV, Filicheva VA |
| Jazyk: |
ruština |
| Zdroj: |
Antibiotiki [Antibiotiki] 1975; Vol. 20 (12), pp. 1061-5. |
| Abstrakt: |
Mutants possessing 3 times higher activity as compared to the initial culture were obtained as a result of selection of active variants of Act. rubiginosonelvolus, a new organism producing rubomycin against the background of variation induced by N-methyl-N1-nitro-N-nitrozoguinidine, diethylsulphate and their combinations. Further selection among the mutants stable to 6-mercaptopurine and riboflavine resulted in obtaining an active culture No. 3912 at least 7 times more active with respect to rubomycin production than the initial soil culture. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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