| Autor: |
Rimkus A; University of Bielefeld, Faculty of Chemistry, P.O. Box 10 01 31, Germany., Sewald N |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2002 Sep 19; Vol. 4 (19), pp. 3289-91. |
| DOI: |
10.1021/ol026557w |
| Abstrakt: |
[reaction: see text] The copper-catalyzed conjugate addition of symmetrical and mixed diorganozinc compounds as well as functionalized diorganozinc cuprates to nitroolefins leads to synthetically versatile nitro compounds in moderate to good yields. Mixed TMSM-organozinc compounds are suitable reagents for conjugate addition, since the TMSM group is not being transferred. Ipso substitution is observed in the absence of a catalytic amount of copper(I) salt. The nitroalkene moiety in 3-nitroacrylates proved to be the predominant Michael acceptor. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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