| Autor: |
Sidorenko IuS; Research Institute of Oncology, the Ministry of Health of the RF, Rostov-on-Don., Zlatnik EIu, Vladimirova LIu, Zakora GI |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy onkologii [Vopr Onkol] 2002; Vol. 48 (2), pp. 202-5. |
| Abstrakt: |
Standard (SCT), autoplasmochemotherapy using cytostatics preincubation with autoplasma (APCT) and autoblood (autohemochemotherapy--AHCT) were compared to evaluate their effects on locally advanced breast tumors. SCT showed marked immunosuppressor effect while APCT and, particularly, AHCT--a sparing one. The use of the latter modalities involved significantly higher levels of active T-, NK- and cytotoxic CD+ 8 cells. A comparison of the latter methods also showed ABCT to yield a better subset balance between T- and B-cells and a higher level of their mitogen response. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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