[Development of pre-hepatic portal hypertension of the rat].
| Autor: | Aller Reyero MA; Facultad de Medicina, Universidad Complutense, Pza. Ramón y Cajal s/n, 28040 Madrid. maaller@med.ucm.es, Diéguez Fernández B, Nava Hidalgo MP, Cuesta Alvaro P, Sánchez García M, Duran Giménez-Rico HJ, Llamas Matías MA, Arias Pérez J |
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| Jazyk: | Spanish; Castilian |
| Zdroj: | Anales de medicina interna (Madrid, Spain : 1984) [An Med Interna] 2002 Jul; Vol. 19 (7), pp. 341-51. |
| Abstrakt: | Objective: A long-term study of the prehepatic portal hypertension model by triple stenosing ligation of the portal vein in the rat. Method: A cluster analysis of the animals in the different evolutive stages of portal hypertension (1 1/2, 6, 12 and 14 months) has been carried out. This analysis has made it possible to identify three homogeneous groups (A, B and C) in relationship to the liver weight. Results: The animals with liver atrophy (group C) show a decrease of body, splenic and testicular weights as well as a higher development of the portosystemic collateral circulation in relation to the A and B groups. Conclusion: The percentage of animals belonging to the group C decrease progressively during the evolution of portal hypertension and those animals corresponding to the group A, in which is superior the liver weight, increase, while the B group does not change. |
| Databáze: | MEDLINE |
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