[Formation of secretory antibodies in experimental influenza infection].

Autor: Agranovskaia EN, Mal'tseva AI, Zlydnikov DM, Krylov VA, Shvartsman IaS
Jazyk: ruština
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1975 Nov (11), pp. 74-7.
Abstrakt: The principal peculiarities attending formation of specific secretory immunity in experimental influenza infection were marked individual variability and a relative autonomicity of accumulation of the secretory antibodies. Functional condition of the secretory immunity before the infection influenced the formation of antibodies in the secretions and the blood sera: when the concentration of the secretory antibodies before the infection constituted 1 : 8--1 : 16, general and secretory antibodies accumulated less intensively. There was a progressive fall of the concentration of the secretory immunoglobulin A in the majority of the volunteers the first 3 weeks after the infection. It is supposed that this process played a significant role in the pathogenesis of influenza complications.
Databáze: MEDLINE