Development of macular pseudoholes: a 36-month period of follow-up.
| Autor: | Varano M; Fondazione per l'Oftalmologia G.B. Bietti, Rome, Italy. md2180@mclink.it, Scassa C, Capaldo N, Sciamanna M, Parisi V |
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| Jazyk: | angličtina |
| Zdroj: | Retina (Philadelphia, Pa.) [Retina] 2002 Aug; Vol. 22 (4), pp. 435-42. |
| DOI: | 10.1097/00006982-200208000-00007 |
| Abstrakt: | Purpose: To assess the changes in visual acuity and macular sensitivity and the possible evolution into a full-thickness macular hole in patients with macular pseudoholes during a 3-year follow-up period. Methods: Twenty-seven eyes (mean age, 61.0 +/- 8.9 years) with macular pseudoholes were enrolled. They were compared with 16 eyes from 16 age-matched control eyes. In each eye with a macular pseudohole, we assessed the Snellen visual acuity and macular sensitivity by scanning laser ophthalmoscopic central (1-2 degrees of the macula, SLO-CM) and paracentral (annular area from 2-7 degrees from the macula, SLO-PM) microperimetry at the time of diagnosis (baseline condition) and every 6 months for 3 years. Results: Eyes with macular pseudoholes at baseline had a significant (P < 0.05) reduction in visual acuity, SLO-CM, and SLO-PM when compared with control eyes. After 12 months of follow-up, no changes in VA, SLO-CM, or SLO-PM were observed in eyes with macular pseudoholes with respect to the baseline values. After 36 months of follow-up, further significant (P < 0.05) decreases in visual acuity, SLO-CM, and SLO-PM were observed. One third of eyes with macular pseudoholes showed an evolution into a full-thickness macular hole. In these eyes, the lowest SLO-CM had been observed at the baseline condition. Conclusion: This study suggests that in the 36-month follow-up period in eyes with macular pseudoholes, there is the possibility of a worsening trend, leading to the development of a full-thickness macular hole. A useful role of the functional assessment by SLO-CM and SLO-PM can be suggested for the clinical diagnosis and the follow-up of macular pseudoholes. |
| Databáze: | MEDLINE |
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