Prostaglandin synthetase and prostaglandin E2 levels in human breast carcinoma.

Autor: Kibbey WE, Bronn DG, Minton JP
Jazyk: angličtina
Zdroj: Prostaglandins and medicine [Prostaglandins Med] 1979 Feb; Vol. 2 (2), pp. 133-9.
DOI: 10.1016/0161-4630(79)90048-x
Abstrakt: Prostaglandin synthetase activity and tissue prostaglandin E2 levels were measured in 53 human breast carcinoma specimens. Each set of data is log-normally distributed. There is a weak but statistically significant correlation between prostaglandin synthetase activity and tissue prostaglandin E2 levels of individual specimens. In addition, in a series of four rat mammary tumors, a rough correlation between prostaglandin synthetase activity and tissue prostaglandin E2 levels was observed. The data suggest a multifactorial explanation for abnormalities of prostaglandin metabolism in human breast cancer.
Databáze: MEDLINE