Duration of antinociceptive action of morphine, methadone and alpha-l-acetylmethadol subcutaneously in rats.

Autor: Wax J, McLean JR, Tessman DK, McCarthy DA, Nuite JA
Jazyk: angličtina
Zdroj: Research communications in chemical pathology and pharmacology [Res Commun Chem Pathol Pharmacol] 1975 Dec; Vol. 12 (4), pp. 613-20.
Abstrakt: The duration of antinociceptive action of alpha-l-acetylmethadol (LAM), determined in the rat tail pinch test, was 6 times that of morphine and 3 times that of methadone. Onset of activity was considerably later after LAM than after morphine or methadone.
Databáze: MEDLINE