| Autor: |
Miziara ID; Stomatology Group, Division of Clinical Otolaryngology, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, Brazil. miz@uol.com.br, Sperandio F, Bohadana SC, Braga N, Romano FR, Miniti A |
| Jazyk: |
angličtina |
| Zdroj: |
Ear, nose, & throat journal [Ear Nose Throat J] 2002 Jul; Vol. 81 (7), pp. 442-8. |
| Abstrakt: |
Cicatricial pemphigoid is a chronic, systemic, autoimmune disease characterized by progressive bullous skin and mucous membrane lesions that tend toward scarring and involution. Manifestations of cicatricial pemphigoid include oral mucosal bullous lesions in 85 to 90% of patients, ocular mucosal lesions in 66%, nasal mucosal lesions in 15 to 23%, and laryngeal involvement in 8 to 21%. We report five cases of cicatricial pemphigoid in which all patients had ENT manifestations--specifically, oral and nasal mucosal involvement. Three of these patients also had laryngeal lesions; one of the three had a large laryngeal ulceration and bullae that caused a laryngeal stenosis and necessitated a tracheostomy. In addition to the five case reports, we also review the literature and discuss the pathogenesis, diagnosis, and treatment of this uncommon disease. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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