| Autor: |
Barhate NB; Department of Chemistry, National Taiwan Normal University, Taipei, Taiwan., Chen CT |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2002 Jul 25; Vol. 4 (15), pp. 2529-32. |
| DOI: |
10.1021/ol026156g |
| Abstrakt: |
[reaction: see text] A series of oxovanadium(IV) complexes derived from tridentate N-ketopinidene-alpha-amino acids were synthesized. They serve as efficient catalysts for the enantioselective oxidative couplings of various 3-, 6-, or 7-substituted 2-naphthols. The best scenario involves the use of a vanadyl complex arising from L-tert-leucine in CCl4. The asymmetric couplings of 2-naphthols can be conducted smoothly at 40-45 degrees C under a stream of gaseous oxygen, leading to 2,2'-dihydroxy-1,1'-binaphthyls in good yields (61-99%) and with enantioselectivities of up to 87%. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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