| Autor: |
Bonné AC; Department of Laboratory Animal Science, Faculty of Veterinary Medicine, Utrecht University, The Netherlands. Bonne@las.vet.uu.nl, den Bieman MG, Gillissen GF, van Zutphen LF, van Lith HA |
| Jazyk: |
angličtina |
| Zdroj: |
Folia biologica [Folia Biol (Praha)] 2002; Vol. 48 (3), pp. 120-3. |
| Abstrakt: |
A genetic linkage map consisting of 258 polymorphic loci has been constructed on the basis of an F2 intercross between the BC/CpbU and LEW/OlaHsd inbred rat strains. When compared to previously published maps a discrepancy was found for rat chromosome 7. The map spans a sex-averaged genetic length of 1790 cM and has an average marker spacing of 7.7 cM. It was estimated that this genetic map is linked to about 90% of the DNA in the rat genome. Because LEW/OlaHsd and BC/CpbU strains differ for dietary cholesterol susceptibility and hepatic copper content, the map is considered to be a valuable tool for studying the genetic background of these complex traits. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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