Autor: |
Patey M, Flament JB, Caron J, Delisle MJ, Delemer B, Pluot M |
Jazyk: |
angličtina |
Zdroj: |
Endocrine pathology [Endocr Pathol] 1996 Winter; Vol. 7 (4), pp. 349-354. |
DOI: |
10.1007/BF02739843 |
Abstrakt: |
The ultimobranchial bodies in human embryos develop from the fourth and fifth branchial pouch complexes along with thymic and parathyroid tissue. They become incorporated within the lateral thyroid lobes and are believed to be involved in the development of C-cells. We report a case of an unusual bilateral thyroid and neck prelaryngeal medullary carcinoma in a 23-year-old male patient who belongs to a multiple endocrine neoplasia type 2a (MEN type 2a) family with thyroid tumors and pheochromocytomas. The medullary carcinoma was located in an abnormal cystic structure that seems to be a remnant of the ultimobranchial body (UBB) in the neck. Within the contralateral thyroid lobe, the medullary carcinoma was associated with C-cell hyperplasia. |
Databáze: |
MEDLINE |
Externí odkaz: |
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