| Autor: |
Brannagan TH 3rd; Department of Neurology, MCP-Hahnemann University, Philadelphia, PA, USA. THB2006@med.cornell.edu, Pradhan A, Heiman-Patterson T, Winkelman AC, Styler MJ, Topolsky DL, Crilley PA, Schwartzman RJ, Brodsky I, Gladstone DE |
| Jazyk: |
angličtina |
| Zdroj: |
Neurology [Neurology] 2002 Jun 25; Vol. 58 (12), pp. 1856-8. |
| DOI: |
10.1212/wnl.58.12.1856 |
| Abstrakt: |
Four patients with chronic inflammatory demyelinating polyneuropathy (CIDP) who were refractory to conventional treatment were treated with high-dose cyclophosphamide (200 mg/kg over 4 days). All improved in functional status and muscle strength. Nerve conduction studies improved in three of four. Other immunomodulatory medications have been discontinued. High-dose cyclophosphamide can be given safely to patients with CIDP and patients with disease persistence after standard therapy may have a response that lasts for over 3 years and results in long-term disease remission. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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