History of head trauma and risk of intracranial meningioma: population-based case-control study.

Autor: Phillips LE; Department of Epidemiology, University of Washington, Seattle, USA., Koepsell TD, van Belle G, Kukull WA, Gehrels JA, Longstreth WT Jr
Jazyk: angličtina
Zdroj: Neurology [Neurology] 2002 Jun 25; Vol. 58 (12), pp. 1849-52.
DOI: 10.1212/wnl.58.12.1849
Abstrakt: A population-based case-control study in western Washington state was performed to assess the relation between head trauma and meningioma. Based on 200 case and 400 control subjects, head trauma was associated with an increased risk of meningioma (odds ratio = 1.83; 95% CI = 1.28, 2.62), especially head traumas occurring 10 to 19 years before reference date (odds ratio = 4.33; 95% CI = 2.06, 9.10). A dose-response relationship was present for number, but not severity, of head traumas. Whether the associations observed in this study are causal remains unclear.
Databáze: MEDLINE