[Complexes of DNA with trivalent metal ions in presence of manganese ions].

Autor: Kas'ianenko NA; Physical Department, St. Petersburg State University, Ul'yanovskaya ul. 1, Petrodvorets, 198904 Russia., Plotnikova LV, Zanina AV, Anderzhanov ASh, Defrenne S
Jazyk: ruština
Zdroj: Biofizika [Biofizika] 2002 May-Jun; Vol. 47 (3), pp. 433-7.
Abstrakt: The interaction of DNA with Fe3+, Al3+, Co(NH3)6(3+) in a solution containing MnCl2 was studied. It was shown that there exists a competition for the binding sites between Mn2+ and Al3+, while the binding of Mn2+ to DNA does not depend on the presence of Fe3+ and Co(NH3)6(3+) in solution. We proposed that Fe3+ and Co(NH3)6(3+) ions prefer to bind to phosphates, and Al3+ ions are capable to bind to the nitrogen bases of DNA.
Databáze: MEDLINE