Barbiturate coma for intracranial hypertension: clinical observations.

Autor: Dereeper E; Department of Anesthesiology, Erasme Hospital, Free University of Brussels, Belgium., Berré J, Vandesteene A, Lefranc F, Vincent JL
Jazyk: angličtina
Zdroj: Journal of critical care [J Crit Care] 2002 Mar; Vol. 17 (1), pp. 58-62.
DOI: 10.1053/jcrc.2002.33032
Abstrakt: Purpose: To determine the neurologic outcome of patients with intracranial hypertension treated with barbiturate-induced coma.
Materials and Methods: The records of 49 patients who were admitted to a 31-bed medicosurgical intensive care unit over a 5-year period in whom a barbiturate coma was induced to control intracranial hypertension were analyzed retrospectively. Analysis included assessment of the response to barbiturate coma and evaluation of the long-term neurologic outcome according to the Glasgow Outcome Scale (GOS).
Results: Intracranial hypertension was caused by head trauma in 28 patients and subarachnoid hemorrhage in 21 patients. Eight of the head trauma patients and 5 of the patients with subarachnoid hemorrhage survived their hospital stay. The survivors were younger than the nonsurvivors, and had a good neurologic status after 1 year (except for 2 patients who died 1 and 3 months after discharge, respectively). There was no significant difference in the Glasgow Coma Score (GCS) on admission between the survivors and the nonsurvivors. The long-term outcome at 1 year was markedly better in the patients who had experienced a subarachnoid hemorrhage than in the trauma patients.
(Copyright 2002, Elsevier Science (USA). All rights reserved.)
Databáze: MEDLINE
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