| Autor: |
Boĭchuk IaA; Bogomolets Institute of Physiology, NAS of Ukraine, Kyiv. mb@serv.biph.kiev.ua, Kopanytsia MV, Lozova NO |
| Jazyk: |
ukrajinština |
| Zdroj: |
Ukrains'kyi biokhimichnyi zhurnal (1999 ) [Ukr Biokhim Zh (1999)] 2001 Sep-Oct; Vol. 73 (5), pp. 114-8. |
| Abstrakt: |
Prolonged incubation with 25 microM homocysteine acid led to initial suppression of the synaptic transmission, which in 6 out of 12 cases was followed by the restoration of the population spike to values 63% from the control. In the rest of experiments, a transient decrease of the population spike amplitude was observed during wash-out of homocysteine acid. Such a pattern suggests that synaptic transmission has special mechanisms for adaptation to increasing concentrations of the excitatory amino acids which are potentially damaging. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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