| Autor: |
Kazanowska B; Klinika Hematologii, i Chorob Rozrostowych Dzieci, AM we Wrocławiu, ul. Bujwida 44, Poland., Wróbel G, Jaworski W, Bogusławska-Jaworska J, Jeleń M, Armata J, Balcerska A, Bubala H, Dluzniewska A, Kołecki P, Kowalczyk J, Kurylak A, Matysiak M, Ploszyńska A, Rokicka-Milewska R, Sońta-Jakimczyk D, Sopylo B, Stańczak E, Stefaniak MJ, Stefańska K, Wysocki M, Gacka M |
| Jazyk: |
polština |
| Zdroj: |
Medycyna wieku rozwojowego [Med Wieku Rozwoj] 2000; Vol. 4 (1 Suppl 2), pp. 57-66. |
| Abstrakt: |
The aim of this study was to analyse the effect of LMB-89 protocol and surgical procedure at initial laparotomy on the outcome in children with abdominal B-cell NHL. The initial surgery intervention was: complete resection (20% pts), subtotal resection (20%), partial resection (4%), biopsy (36%). Postoperative complications occurred in 5 children. Complete recovery (CR) was achieved in 92% pts. There were 4% non responder patients. Two patients died before CR evaluation (tumour lysis syndrome; bleeding and multi organ failure after initial surgery). One patient died in CCR from sepsis probably influenced by the previous local operation. 10.8% patients relapsed. The estimate EFS for all patients with AB-NHL is 81%, 85% for stage III and 73% for stage IV. Major surgery in advanced stages is not recommended since it delays chemotherapy and fails to improve overall survival. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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