Helicobacter pylori primary resistance to metronidazole and clarithromycin in Brazil.

Autor: Prazeres Magalhães P; Laboratory of Research in Bacteriology, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., De Magalhães Queiroz DM, Campos Barbosa DV, Aguiar Rocha G, Nogueira Mendes E, Santos A, Valle Corrêa PR, Camargos Rocha AM, Martins Teixeira L, Affonso de Oliveira C
Jazyk: angličtina
Zdroj: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2002 Jun; Vol. 46 (6), pp. 2021-3.
DOI: 10.1128/AAC.46.6.2021-2023.2002
Abstrakt: Helicobacter pylori resistance to metronidazole was detected in 107 (52.97%) of 202 strains. Twenty (9.85%) strains, 18 of them harboring 23S ribosomal DNA mutations, were resistant to clarithromycin. Metronidazole resistance was associated with female gender. Resistance to metronidazole and resistance to clarithromycin were associated. Increasing clarithromycin resistance rates were observed over time.
Databáze: MEDLINE