The association of pre-eclampsia with the Duffy negative phenotype in women of West African descent.

Autor: Velzing-Aarts FV; Pathology and Laboratory Medicine, Groningen University Hospital, The Netherlands., van der Dijs FP, Muskiet FA, Duits AJ
Jazyk: angličtina
Zdroj: BJOG : an international journal of obstetrics and gynaecology [BJOG] 2002 Apr; Vol. 109 (4), pp. 453-5.
DOI: 10.1111/j.1471-0528.2002.01181.x
Abstrakt: Objective: To investigate whether pre-eclampsia in Curaçao is associated with the Duffy negative phenotype.
Design: Retrospective study.
Results: Women with a history of pre-eclampsia had a higher Duffy negative phenotype frequency compared with women with a history of uncomplicated pregnancies (52.8 vs 27.3%, respectively; odds ratio 2.98; 95% CI 1.40-6.32; P = 0.004).
Conclusions: Pre-eclampsia is associated with the Duffy negative phenotype in women of West-African descent in the island of Curaçao.
Databáze: MEDLINE
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