Autor: |
Kuznetsov SI, Barashkova LN, Burkova NV, Eĭsmont IuA, Korosteleva IuG, Kanaev PA, Nosikova EV, Ogurtsov RP, Tiukavin AI |
Jazyk: |
ruština |
Zdroj: |
Patologicheskaia fiziologiia i eksperimental'naia terapiia [Patol Fiziol Eksp Ter] 2002 Jan-Mar (1), pp. 18-20. |
Abstrakt: |
In modeling acute diphtheric toxemia in guinea pigs, the authors propose to perform hemosorption using selective sorbents under continuous introduction of antitoxic immune sera into extracorporeal contour in front of sorption column. Combination of hemosorption with serotherapy in the same time interval may be denoted as serosorption. As specific sorbents, affine preparations imasorb A-700 and Imasorb G-700 were used. They selectively eliminate from the blood flow CIC produced by diphtheric toxin (anatoxin) and antitoxic rabbit and horse antibodies. Changes in the titers of the diphtheric toxin (anatoxin) and CIC in blood evidence for efficiency of selective sorbents were confirmed by immunohistochemical analysis of the preparations' granules after hemoperfusion. |
Databáze: |
MEDLINE |
Externí odkaz: |
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