Mox homeobox expression in muscle lineage of the gastropod Haliotis asinina: evidence for a conserved role in bilaterian myogenesis.

Autor: Hinman VF; Deparment of Zoology and Entomology, University of Queensland 4072, Australia., Degnan BM
Jazyk: angličtina
Zdroj: Development genes and evolution [Dev Genes Evol] 2002 Apr; Vol. 212 (3), pp. 141-4. Date of Electronic Publication: 2002 Mar 13.
DOI: 10.1007/s00427-002-0223-6
Abstrakt: Mox homeobox genes are expressed during early vertebrate somitogenesis. Here we describe the expression of Has-Mox, a Mox gene from the gastropod Haliotis asinina. Has-Moxis expressed in the trochophore larva in paraxial mesodermal bands. During larval development, Has-Mox expression remains restricted to mesodermal cells destined to form adult muscle in the foot. This restricted expression of Has-Mox in Haliotis is similar to that observed for vertebrate Mox genes, suggesting a conserved role in myogenesis in deuterostomes and lophotrochozoans. In contrast, Mox is not expressed in muscle lineages in the ecdysozoan representatives Caenorhabditis elegans or Drosophila; the C. elegansgenome has lost Mox altogether. Electronic supplementary material to this paper can be obtained by using the Springer Link server located at http://dx.doi.org/10.1007/s00427-002-0223-6.
Databáze: MEDLINE