| Autor: |
Gu HH; Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ 08543-4000, USA. henry.gu@bms.com, Iwanowicz EJ, Guo J, Watterson SH, Shen Z, Pitts WJ, Dhar TG, Fleener CA, Rouleau K, Sherbina NZ, Witmer M, Tredup J, Hollenbaugh D |
| Jazyk: |
angličtina |
| Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2002 May 06; Vol. 12 (9), pp. 1323-6. |
| DOI: |
10.1016/s0960-894x(02)00132-4 |
| Abstrakt: |
A series of novel amide-based small molecule inhibitors of inosine monophosphate dehydrogenase is described. The synthesis and the structure-activity relationships (SARs) derived from in vitro studies are presented. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
Full Text from ScienceDirect