Autor: |
Hotsuliak IaM; A.A. Bogomoletz Institute of Physiology, National Academy of Science of Ukraine, Kiev., Berdyieva TK, Libert SV |
Jazyk: |
ukrajinština |
Zdroj: |
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) [Fiziol Zh (1994)] 2002; Vol. 48 (1), pp. 98-101. |
Abstrakt: |
We studied the effects of blockers of the T-type Ca2+ channels on resumption of meiosis and spontaneous meiotic maturation of murine ovarial oocytes in vitro. We found that the efficiency of suppression of oocyte maturation by blockers of the Ca2+ channels increases in the following succession: amiloride hydrochloride, mebifradil, NiCl2. It is supposed that there is a possibility to use blockers of the T-type Ca2+ channels for creation of new combined intrauterine contraceptives. |
Databáze: |
MEDLINE |
Externí odkaz: |
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