| Autor: |
Alekseeva TN; Institute of Pharmacology, Russian Academy of Medical Sciences, Baltiiskaya ul. 8, Moscow, 125315 Russia., Durnev AD, Kulakova AV, Oreshchenko AV, Samusenok LV, Ogarkov BN, Seredenin SB |
| Jazyk: |
ruština |
| Zdroj: |
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2001 Nov-Dec; Vol. 64 (6), pp. 56-9. |
| Abstrakt: |
The chromosome aberration assay in the bone marrow cells of C57BL/6 mice showed that melanin pigment (MP) in a dose range from 0.01 to 10 mg/kg does not influence the clastogenic effect of dioxidine (200 mg/kg, i.p.), while reducing the clastogenic effect of cyclophosphamide (20 mg/kg, i.p.) by a factor of 1.5-4 in various treatment regimes depending on the mutagen injection time. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
