Analysis of N-glycosyl bond length in crystal structures of nucleosides and nucleotides.

Autor: Lo A, Shefter E, Cochran TG
Jazyk: angličtina
Zdroj: Journal of pharmaceutical sciences [J Pharm Sci] 1975 Oct; Vol. 64 (10), pp. 1707-10.
DOI: 10.1002/jps.2600641029
Abstrakt: A relationship was found between the N-glycosyl bond length in beta-nucleosides and nucleotides and the spatial relationship of this bond with respect to the lone-pair orbitals on the furanose ring oxygen. This relationship may be relevant to the geometry involved in the hydrolysis of the glycosidic bond.
Databáze: MEDLINE