| Autor: |
Martinelli C; Infectious Diseases Unit, Azienda Ospedaliera Careggi, Florence, Italy. fohle@tin.it, Farese A, Mistro AD, Giorgini S, Ruffino I |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of the European Academy of Dermatology and Venereology : JEADV [J Eur Acad Dermatol Venereol] 2001 Nov; Vol. 15 (6), pp. 568-9. |
| DOI: |
10.1046/j.1468-3083.2001.00288.x |
| Abstrakt: |
Anogenital condylomata acuminata are the most frequent clinical manifestation of genital human papillomavirus (HPV) infection. Association between human immunodeficiency virus (HIV) and HPV infections is frequent (range: 26-60% in males). Topical cidofovir (a nucleotide analogue antiviral drug active against a broad range of DNA viruses) is a potential treatment for anogenital warts in immunocompromised patients. We treated three HIV-infected patients with HPV perianal condylomas with topical 1% cidofovir in flexible collodion once a day for 2 weeks. The treatment resulted in complete clearance of the HPV lesions. The patients experienced mild transient erythema without any other side-effects. None of the patients relapsed during the 10-14-month follow-up period. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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