| Autor: |
Kulakov IuK; N. F. Gamaleya Institute of Epidemiology and Microbiology, Russian Academy of Medical Sciences., Zheludkov MM |
| Jazyk: |
ruština |
| Zdroj: |
Molekuliarnaia genetika, mikrobiologiia i virusologiia [Mol Gen Mikrobiol Virusol] 2001 (4), pp. 8-12. |
| Abstrakt: |
The authors review published reports on the molecular bases of Brucella virulence, including type IV secretion proteins, S-lipopolysaccharide biosynthesis enzymes (O-antigen), regulatory proteins of various systems, and cellular metabolism proteins. High efficiency of modified transposon mutagenesis technique (selective labeled transposon mutagenesis) in search for virulence genes is shown. Analysis of DNA sequences of Brucella genome promotes identification of new virulence factors. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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