| Autor: |
Utz N; Department of Neurology, City Hospital of Merheim, Cologne, Germany. NUtz695191@aol.com, Kinkel B, Hedde JP, Bewermeyer H |
| Jazyk: |
angličtina |
| Zdroj: |
Neuroradiology [Neuroradiology] 2001 Dec; Vol. 43 (12), pp. 1059-62. |
| DOI: |
10.1007/s002340100616 |
| Abstrakt: |
Reversible posterior leukoencephalopathy syndrome (PLS) is characterized by headache, altered mental function, visual disturbances and seizures. Neuroimaging studies suggest a white-matter oedema, predominantly in the posterior parietal-temporal-occipital regions of the brain. We present the case of a 30-year-old woman who had suffered her first attack of acute intermittent porphyria (AIP). Following 1 week of abdominal pain she developed several generalized seizures, and hallucinations, and exhibited a progressive deterioration of the consciousness. T2-weighted images, especially fluid-attenuated inversion recovery (FLAIR) sequences showed bilateral lesions in the posterior frontal, parietal and occipital cortex and subcortical white matter. Following treatment with haematin and a high carbohydrate diet the patient's condition improved. Follow-up magnetic resonance imaging (MRI) revealed complete resolution of the lesions. To our knowledge, this is the first report concerning a completely reversible PLS in AIP. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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