| Autor: |
Pereira SR; Laboratory of Viral Pathogenesis and Diagnosis, Department of Virology, Professor Paulo de Góes Institute of Microbiology, Center for Health Sciences, Federal University of Rio de Janeiro, Brazil. silviareginafgp@ig.com.br, Guimarães MA, Neto LV, Segenreich D, Varella RB, Antunes Chagas VL, Câmara FP |
| Jazyk: |
angličtina |
| Zdroj: |
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases [Braz J Infect Dis] 2001 Aug; Vol. 5 (4), pp. 183-91. |
| DOI: |
10.1590/s1413-86702001000400004 |
| Abstrakt: |
Two different procedures for inoculation of HSV on corneas of BALB/c mice were evaluated. The first was by the use of HSV suspensions directly on the corneas and the other was after corneal scarification. Animals by this later method presented greater morbidity and mortality than those of first group, suggesting that inoculation of HSV without scarification of the cornea should be the method of choice for the study of HSV ophthalmic infection. This model showed also be an efficient experimental system to testing antiviral drugs. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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