Multiple myeloma-associated amyloidosis manifesting as fulminant hepatic failure.

Autor: Ales NC; Department of Internal Medicine, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA., Daniels JT, Frizell ER, Koff JM, Kaplan KJ, Wortmann GW
Jazyk: angličtina
Zdroj: Southern medical journal [South Med J] 2001 Oct; Vol. 94 (10), pp. 1036-8.
Abstrakt: We report a case of amyloidosis associated with K light chain multiple myeloma in a 42-year-old African American man. The patient initially had mild dyspepsia, which rapidly progressed to include anorexia, fulminant hepatic failure, and death within 9 weeks. This is only the fourth reported case of hepatic failure from myeloma-associated amyloidosis and the second reported case of light chain myeloma with amyloidosis resulting in a progressive clinical course of hepatic failure. Our patient was unique in that, despite severe disease, he had mild symptoms without laboratory abnormalities until 2 weeks prior to death.
Databáze: MEDLINE
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