The penetration of cefoperazone and sulbactam into the lumbar intervertebral discs.

Autor: Köroğlu A; Department of Neurosurgery, Faculty of Medicine, Selçuk University, Konya, Turkey., Acar O, Ustün ME, Tiraş B, Eser O
Jazyk: angličtina
Zdroj: Journal of spinal disorders [J Spinal Disord] 2001 Oct; Vol. 14 (5), pp. 453-4.
DOI: 10.1097/00002517-200110000-00014
Abstrakt: Six patients received 1 g and six other patients received 2 g of cefoperazone and sulbactam 15 minutes before lumbar disc surgery. Liquid chromatographic analysis of disc tissue revealed that only patients receiving the 2-g dose had mean tissue levels above the minimum inhibitory concentration for Staphylococcus aureus and epidermidis.
Databáze: MEDLINE