[Absorption kinetics of C14-GABA and its vitamin B conjugates in isolated bovine retina].

Autor: Rozanova ZA; Institute of Eye Diseases and Tissue Therapy named by Filatov, AMS of Ukraine, Odessa.
Jazyk: ukrajinština
Zdroj: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) [Fiziol Zh (1994)] 2001; Vol. 47 (4), pp. 63-6.
Abstrakt: Absorption by the bovine retina of physiological concentration of PLP-GABA increase clearing 2-32 minutes of incubation in difference of GABA and its non metabolic preparations, which store up as much as possible in first minutes: picamilon > PLP-GABA > GABA > panthogam > biotinil-GABA. Kinetics of transport of GABA and its preparations into retina has a complex character. By the growth of concentration from 33 mM to 528 mM, it is linear for picamilion, showing diffusion, and not linear for GABA, PLP-GABA and panthogam, showing differently systems of its transport. And only GABA transport is activated by Na-ions.
Databáze: MEDLINE