| Autor: |
Kariakin OB, Sviridova TV, Tsodikova LB, Grishin GN, Sergeeva TN, Perekhrest MA, Donichkina EA |
| Jazyk: |
ruština |
| Zdroj: |
Urologiia (Moscow, Russia : 1999) [Urologiia] 2001 Jul-Aug (4), pp. 26-9. |
| Abstrakt: |
Three-month treatment with casodex (150 mg/day) of untreated patients with locally advanced and/or advanced cancer of the prostate is well tolerated. The only side effect encountered in 9(60%) patients was temporary breast painfulness and swelling. Subjective effects consisted of higher activity (in 40% of patients), pain relief (in 33.3%), improved urination (in 80%). Objective effects comprise: reduction of prostate-specific antigen in 14(93.3%) patients by 150.4 ng/ml at the average; a rise in testosterone concentration in 12(80%) patients; regression of the tumor by more than 50% in 5(33.3%) patients; stabilization and partial regression of regional metastases (1 case); stabilization of distant metastases (3 of 4 cases). One patient showed progression of bone metastasizing in partial local regression of the tumor. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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