| Autor: |
Swingle KF, Scherrer RA, Grant TJ |
| Jazyk: |
angličtina |
| Zdroj: |
Archives internationales de pharmacodynamie et de therapie [Arch Int Pharmacodyn Ther] 1975 Apr; Vol. 214 (2), pp. 240-9. |
| Abstrakt: |
The antiinflammatory activity of R-803 (alpha-methyl-3-phenyl-7-benzofuranacetic acid), a new nonsteroidal drug, has been demonstrated. The oral administration of R-803 inhibits carrageenan-induced edema of the rat's paw, ultraviolet-induced erythema of guinea-pig skin, adjuvant-induced and 6-sulfonamidoindazole-induced arthritides of the rat at doses in the range of 1.0 to 6.0 mg/kg. It also inhibits the cotton pellet-induced granuloma in the rat at higher doses. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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