Autor: |
Driniaev VA; Pharmbiomed Research Centre of Biology, Moscow., Mosin VA, Krugliak EB, Sterlina TS, Viktorov AV, Tsyganova VG, Korystova AF, Grichenko AS, Zenchenko KI, Kokoz IuM |
Jazyk: |
ruština |
Zdroj: |
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] [Antibiot Khimioter] 2001; Vol. 46 (5), pp. 13-6. |
Abstrakt: |
A natural avermectin complex, aversectin C, was shown to be capable of exerting selective cytostatic effect. It killed proliferating neuroblastoma B 103 cells but was non-toxic for differentiated cells of this culture. The activity of aversectin C was related neither to activation of the GABA alpha-receptors nor to their blocking and was at a large extent due to the action of avermectin A1, a component of aversectin C. |
Databáze: |
MEDLINE |
Externí odkaz: |
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