| Autor: |
Ryabukhin IA; V. P. Serbskii Research Center of Social and Forensic Medicine, Moscow., Artemkina IV, Gurina OI, Sergienko VI, Chekhonin VP |
| Jazyk: |
angličtina |
| Zdroj: |
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2001 May; Vol. 131 (5), pp. 502-4. |
| DOI: |
10.1023/a:1017904805547 |
| Abstrakt: |
Enzyme immunoassay showed penetration of two glia-specific antigens, glial fibrillar acid protein GFAP and specific brain glycoprotein alpha(2)GP, through the blood-brain barrier in rats treated with toxic doses of sodium barbital. The permeability of the blood-brain barrier was completely normalized 3 days after treatment. This method can be used in clinical practice for evaluation of the severity of impairment and dynamics of normalization of blood-brain barrier properties during acute intoxication with barbiturates. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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