Autor: |
Mikovskaia OI; Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow., Vetrilé LA, Trekova NA, Basharova LA, Evseev VA |
Jazyk: |
ruština |
Zdroj: |
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova [Zh Vyssh Nerv Deiat Im I P Pavlova] 2001 Mar-Apr; Vol. 51 (2), pp. 190-6. |
Abstrakt: |
The effect of active immunization with conjugated serotonin-protein on the "open-field" behaviour and passive avoidance conditioning was studied in genetically different mice strains (C57BL/6 and BALB/c). The obtained immunophysiological effects of serotonin antibodies depended on genetically determined characteristics of animal behaviour. Serotonin antibodies altered rearing and crossings of the "open-field" center and retention of passive avoidance learning in C57BL/6 mice. The active immunization with conjugated serotonin-protein of BALB/c mice resulted in modulation of the "open-field" latency and both training and testing of passive avoidance behaviour. |
Databáze: |
MEDLINE |
Externí odkaz: |
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