| Autor: |
Gougeon ML; Département SIDA et Rétrovirus, Institut Pasteur, Paris, France., Rouzioux C, Liberman I, Burgard M, Taoufik Y, Viard JP, Bouchenafa K, Capitant C, Delfraissy JF, Levy Y |
| Jazyk: |
angličtina |
| Zdroj: |
AIDS (London, England) [AIDS] 2001 Sep 07; Vol. 15 (13), pp. 1729-31. |
| DOI: |
10.1097/00002030-200109070-00018 |
| Abstrakt: |
We report the long-term outcome of 27 HIV-infected patients treated for over 3 years with IL-2 and binucleoside analogues. These patients experienced a sustained increase in CD4 cells and a decrease of proviral DNA with infrequent IL-2 cycles. In three cases, virus could not be isolated from activated peripheral cells. A high frequency of HIV-1-specific memory CD4 T cells was found in the patients studied. IL-2 maintains specific effector cells and reduces the pool of infected cells in patients, albeit treated only with binucleosides. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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