Heterotopic neuroglial tissue causing airway obstruction in the newborn.
| Autor: | Behar PM; Department of Pediatric Otolaryngology, The Children's Hospital of Buffalo, 219 Bryant St, Buffalo, NY 14222, USA. pmbehar@aol.com, Muller S, Gerber ME, Todd NW |
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| Jazyk: | angličtina |
| Zdroj: | Archives of otolaryngology--head & neck surgery [Arch Otolaryngol Head Neck Surg] 2001 Aug; Vol. 127 (8), pp. 997-1002. |
| DOI: | 10.1001/archotol.127.8.997 |
| Abstrakt: | Background: Heterotopic neuroglial (brain) tissue is a rare cause of airway obstruction in newborns. Fewer than 30 cases have been reported in the English literature. Brain heterotopias can mimic more common congenital anomalies of the head and neck. Objective: To review our experience in the diagnosis and treatment of children with heterotopic pharyngeal neuroglial tissue. Design: Case series. Setting: Tertiary care children's hospital. Patients: Four newborns with airway obstruction caused by heterotopic neuroglial tissue. Results: All patients were infants (3 full-term girls and a 32 weeks' gestation boy) who had airway obstruction in the newborn period. All patients underwent preoperative computed tomography and magnetic resonance imaging, which revealed a heterogeneous mass involving the pharynx, neck, and parapharyngeal space. Bony deformities of the skull base and mandible were present in all patients, although intracranial connection was absent. Multiple surgical procedures were performed in all 4 patients. Tracheotomy was performed in 2 patients, gastrostomy tube placement was required in 3, and a nasopharyngeal tube was used in 1. Combined cervicofacial and transoral approaches were used for resection, preserving vital structures. Histopathologic evaluation revealed mature glial tissue and choroid plexus-like structures. Conclusions: Heterotopic neuroglial tissue must be considered in the differential diagnosis of airway obstruction in the newborn. Management is surgical resection, with attention to vital structures and function-analogous to surgery for lymphangioma. Multiple surgical procedures might be necessary in the treatment of these patients. |
| Databáze: | MEDLINE |
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